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May 23 – 25, 2023 | Cleveland, Ohio

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Tuesday, May 23 – Day One
Harrington Scholar Programming: 6:00 PM – 8:00 PM ET 

6:00 PM -

8:00 PM

Casual Scholar Reception & Dinner

By Invitation Only

Wednesday, May 24 – Day Two
Keynote Address & Reception: 4:00 PM – 6:15 PM ET 
Harrington Scholar Programming: 7:30 AM – 8:45 PM ET BY INVITATION ONLY

8:00 AM -

2:50 PM

Scholar Project Team Meetings

By Invitation Only

8:30 AM –

9:30 AM

Scholar Workshop One

Presented by Jim Bryson, PhD & William Greenlee, PhD

Title: Target Compound Profiles for Drug Discovery

A Target Compound Profile is a set of desired properties of a molecule expected to be met at a defined stage of a Scholar program. Harrington Discovery Institute has created formats for Target Compound Profiles for both small molecules and large molecules. These documents help support decisions about advancing and resourcing Scholar programs and ensure that team members have a common understanding of the profiles required for success. In this presentation, we will present and discuss sample profiles for hits, leads, development candidates and products. 

10:00 AM –

11:00 AM

Scholar Workshop Two

Presented by Bernard Cambou, PhD, MBA & Jan Rosenbaum, PhD

Title: How to Best Position Your Novel Drug Opportunity to Attract “Commercial” Interest

The mission of Harrington Discovery Institute’s Scholar Award programs is to advance academic discoveries in areas of unmet  therapeutic need into medicines for the benefit of society. In order to do that, scientists must not only be developing disruptive therapies, but should also be able to communicate their value proposition to  investors and partners who will be able to help bring those therapies to market. In this workshop, we will discuss the elements of the value proposition, how to de-risk the development plan from target validation through clinical development. We hope to encourage academic investigators to present their value proposition to investors and commercial partners in the context of multi-level differentiating factors.

11:00 AM –

2:00 PM

Poster Session

By Invitation Only

4:00 PM -

6:15 PM

6:30 PM -

8:45 PM

Keynote Address & Reception

Open to All Guests

Tinkham Veale University Center

Ballroom A/B on Floor 2

Jean Bennett, MD, PhD

University of Pennsylvania

2023 Harrington Prize Co-Recipient

Title: Genes as Medicine: From Concept to Practice   

   Click for Bio   

Private Dinner & Remarks

By Invitation Only

Robert Lefkowitz, MD

Duke University Medical Center

   Click for Bio   

Thursday, May 25 – Day Three
Harrington Scholar Programming: 7:30 AM – 4:25 PM ET BY INVITATION ONLY

7:30 AM -

8:30 AM

Continental Breakfast

By Invitation Only

8:30 AM -

11:45 AM

8:45 AM -

9:43 AM

Scholar Presentations (PRIVATE SESSION)

By Invitation Only

Li Lan, MD, PhD

Massachusetts General Hospital

Title: Targeting mRNA Methyltransferase in Cancer Therapy

   Click for Bio   

Loren Walensky, MD, PhD

Dana-Farber Cancer Institute

Title: Multimodal Targeting of Chemo-Resistant Cancer by Stapled Peptide PROTACs

   Click for Bio   

Carolyn Lee, MD, PhD

Stanford University

Title: Design, Synthesis and Validation of Novel RET Inhibitors to Treat Cutaneous Squamous Cell Carcinoma

   Click for Bio   

9:45 AM -

10:20 AM


10:25 AM -

11:43 AM

Bernd Schnabl, MD

University of California, San Diego

Title: Bacteriophage Therapy to Treat Alcoholic Hepatitis

   Click for Bio   

James Hagood, MD

University of North Carolina

Title: Thy-1 Molecular Mimicry as a Therapeutic Strategy for Pulmonary Fibrosis

   Click for Bio   

Burton Dickey, MD

University of Texas MD Anderson Cancer Center

Title: Targeting Syt2 to Prevent Airway Mucin Hypersecretion

   Click for Bio   

12:00 PM -

1:30 PM

2:12 PM -

4:20 PM

Luncheon & Presentation

By Invitation Only

Scholar Presentations (PRIVATE SESSION)

By Invitation Only

2:12 PM -

3:10 PM

Diana Farmer, MD

University of California, Davis

Title: Engineered Human Placenta-Derived Mesenchymal Stem / Stromal Cells for the Treatment of Acquired Spinal Cord Injury

   Click for Bio   

Ed Grabczyk, PhD

LSU Health Sciences Center in New Orleans

Title: Small Molecule Induced Skipping of MLH3 Exon Seven to Slow Progression of DNA Repeat Expansion Disorders

   Click for Bio   

Michael Lin, MD, PhD

Stanford University

Title: Potent and Selective Protease Inhibitors for Treatment of COVID-19 and Future Coronavirus Diseases

   Click for Bio   

3:12 PM -

3:20 PM

Stretch Break

3:22 PM -

4:20 PM

David Myung, MD, PhD

Stanford University

Title: Regenerative Matrix Therapy for the Cornea

   Click for Bio   

Xin Qi, PhD

Case Western Reserve University

Title: Development of ATAD3A Peptide Inhibitors to Treat Alzheimer’s Disease

   Click for Bio   

Nabil Alkayed, MD, PhD

Oregon Health and Science University

Title: GPR39 as a Therapeutic Target in Vascular Cognitive Impairment and Dementia (VCID)

   Click for Bio    

4:20 PM -

4:25 PM

Closing Remarks

Seth Field, MD, PhD



2021-2022 Annual Publication

Coming Soon >
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