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SCIENTIFIC SYMPOSIUM

2022 Harrington

Scientific Symposium

May 25-26, 2022

 

** Plenary sessions for the Symposium will be broadcast in this space. No additional access links are needed. **

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2022 SCIENTIFIC SYMPOSIUM AGENDA 
MAY 25 - MAY 26
* Note: Meeting will be held in Eastern Time zone.

Wednesday, May 25 - Day One
Plenary Session: 10:00am – 12:15pm ET 
OPEN TO ALL GUESTS
Private Session: 12:30pm – 3:00pm ET CLOSED SESSION (Scholars, Partners, Advisors only)

10:00am –10:15am

Welcome

Jonathan S. Stamler, MD

President, Harrington Discovery Institute

Robert S. & Sylvia K. Reitman Family Foundation Distinguished Chair in Cardiovascular Innovation

Introduction to Ronald G. Harrington

Daniel I. Simon, MD

President, Academic & External Affairs and Chief Clinical & Scientific Officer, University Hospitals 
Ernie and Patti Novak Distinguished Chair in Health Care Leadership at University Hospitals

Remarks

Ronald G. Harrington

Philanthropist and Entrepreneur

10:15am –10:50am

Introduction to Keynote Address

Jonathan S. Stamler, MD

Keynote Address

Jeffrey Leiden, MD, PhD

Title: Discovering Transformative Medicines: The Vertex Innovation Model

Executive Chairman, Vertex Pharmaceuticals

10:50am –11:00am

Introduction of Cliff Megerian, MD 

Jonathan S. Stamler, MD

UH Remarks

Cliff A. Megerian, MD, FACS

CEO, University Hospitals

Jane and Henry Meyer Chief Executive Officer Distinguished Chair

11:00am –11:45am

The Harrington Impact on Alzheimer’s Disease:

Novel Pathways and Therapies

Moderator:

Andrew Pieper, MD, PhD

Director, Center for Brain Health Medicines, Harrington Discovery Institute

Investigator, Harrington Discovery Institute

Morley-Mather Chair in Neuropsychiatry

 

Panel Members:

Jerri Rook, PhD

Vanderbilt University

2015 ADDF-Harrington Scholar

Stephen Strittmatter, MD, PhD 

Yale University

2020 Harrington Scholar-Innovator

 

 

 

Jonathan Stamler, MD

Case Western Reserve University / University Hospitals

11:45am –12:10pm

Introduction of 2022 Harrington Prize Recipients

Hossein Ardehali, MD, PhD

Northwestern University

President, American Society for Clinical Investigation

2022 Harrington Prize Remarks

James Crowe, MD

Vanderbilt University

Michel Nussenzweig, MD, PhD

The Rockefeller University

 

12:15pm –12:30pm

BREAK & END OF DAY 1 PLENARY SESSION

Scholar Scientific Presentations are delivered in a Closed Session.

Scholars, Partners, Advisors only. 

12:30pm –12:35pm

Introduction to Scholar Presentations and Advisory Panels

Moderator:

Seth Field, MD, PhD

Director, Physician-Scientist Programs

Investigator, Harrington Discovery Institute

12:35pm –3:00pm

Rizwan Haq, MD, PhD

Title: A Small Molecule that Targets Cancers with Dysregulated KEAP-NRF2 Signaling

2020 Harrington Scholar-Innovator

Dana-Farber Cancer Institute

 

 

 

Jill Smith, MD

Title: Targeted Nanoparticle for Early Diagnosis and Treatment of Pancreatic Cancer

2021 Harrington Scholar-Innovator

Georgetown University

 

 

 

Joseph Contessa, MD, PhD

Title: Development of OST Inhibitors for the Treatment of Lung Cancer

2021 Harrington Scholar-Innovator

Yale University

 

 

 

John Chorba, MD

Title: Inhibiting PCSK9 Self-Proteolysis to Treat Atherosclerosis

2021 Harrington Scholar-Innovator

University of California, San Francisco

 

 

 

Kyu Rhee, MD, PhD

Title: Pantothenamides Against Tuberculosis: Selective Inhibitors of the Mycobacterium Tuberculosis Tubercle

2020 Harrington Scholar-Innovator

Weill Cornell Medicine

 

 

 

Jennifer Chen, MD

Title: Targeting Acid Ceramidase to Reverse Fibrosis

2021 Harrington Scholar-Innovator

University of California, San Francisco

 

 

 

Aaron Schimmer, MD

Title: Development of Novel Inhibitors of Human Mitochondrial Protease, ClpP

2021 Harrington Scholar-Innovator

University of Toronto

3:00pm 

Day 1 Closing Remarks

Seth Field, MD, PhD

Thursday, May 26 - Day Two
Plenary Session: 10:00am – 11:30am ET OPEN TO ALL GUESTS
Private Session: 12:00pm – 2:10pm ET CLOSED SESSION (Scholars, Partners, Advisors only)

10:00am –10:10am

Welcome Back

Seth Field, MD, PhD

Director, Physician-Scientist Programs

Investigator, Harrington Discovery Institute

10:10am –10:35am

Introduction to Scholar Experience Presentations

Diana Wetmore, PhD

Vice President of Therapeutics Development, Harrington Discovery Institute

Rosa Bacchetta, MD

Stanford University

2019 Harrington Scholar-Innovator

Marc Wein, MD, PhD

Massachusetts General Hospital

2018 Harrington Scholar-Innovator

10:35am –11:25am

Introduction to Panel Session 

Lenka Fedorkova, PhD

Vice President, Business Development and Strategic Alliance Management

Creating a Value Proposition that Attracts Investment:

A Panel Session with Harrington Investment Advisors

Moderator:

Rebecca Braun

Consultant, Harrington Discovery Institute

 

Panel Members:

Graeme Martin, PhD

Chief Investment Officer, ALSA Ventures

Member, Harrington Discovery Institute Investment Advisory Board

John Rice, PhD

Life Sciences Managing Director, CincyTech, LLC.

Chair, Harrington Discovery Institute Investment Advisory Board

 

Jesse Treu, PhD

Partner Emeritus, Domain Associates

Member, Harrington Discovery Institute Investment Advisory Board

11:25am –12:00pm

BREAK & END OF DAY 2 PLENARY SESSION

Scholar Scientific Presentations are delivered in a Closed Session.

Scholars, Partners, Advisors only. 

12:00pm –12:05pm

Introduction to Scholar Presentations and Advisory Panels

Moderators:

Andrew Pieper, MD, PhD

Director, Center for Brain Health Medicines, Harrington Discovery Institute

Investigator, Harrington Discovery Institute

Morley-Mather Chair in Neuropsychiatry

Atul Chopra, MD, PhD

Investigator, Harrington Discovery Institute

12:05pm –2:10pm

Stephen Martin, PhD

Title: New Approach for Neuroprotection of Photoreceptors by Targeting TMEM97/σ2R

2019 Gund Harrington Scholar

University of Texas at Austin

 

 

 

Donald Weaver, MD, PhD, FRCP(C)

Title: Design and Development of Small Molecular Therapeutics Targeting the Immunopathy of Alzheimer’s Disease

2020 Harrington Scholar-Innovator

University Health Network

 

 

Xinnan Wang, MD, PhD

Title: Targeting Mitophagy for Treating Parkinson’s Disease

2021 Harrington Scholar-Innovator

Stanford University

 

 

Timothy Yu, MD, PhD

Title: ASO Treatment for KCNT1-Associated Developmental Epileptic Encephalopathy

2020 Harrington Scholar-Innovator

Boston Children's Hospital

 

Michael Holtzman, MD

Title: A New Drug to Correct Epithelial Stem Cell Reprogramming in Respiratory Disease

2020 Harrington Scholar-Innovator

Washington University St. Louis

 

 

Toren Finkel, MD, PhD

Title: Generating Small Molecules that Boost NAD+ Levels for Age-Related Diseases

2021 Harrington Scholar-Innovator

University of Pittsburgh

2:10pm 

Day 2 Closing Remarks

Jonathan S. Stamler, MD

President, Harrington Discovery Institute

RESOURCE CENTER

Coming Soon >

2020-2021 Annual Publication